Profile of D-Dimer Levels in Patients Confirmed Positive for COVID-19 at the Indonesian Christian University Hospital
Danny Ernest Jonas Luhulima *
Department of Clinical Pathology, Faculty of Medicine, Universitas Kristen Indonesia, Indonesia and General Hospital, Universitas Kristen Indonesia, Indonesia.
Agriva Taufan Vicani Damanik
Department of Clinical Pathology, Faculty of Medicine, Universitas Kristen Indonesia, Indonesia.
Tiroy Sari B. Simanjuntak
General Hospital, Universitas Kristen Indonesia, Indonesia and Department of Internal Medicine, Faculty of Medicine, Universitas Kristen Indonesia, Indonesia.
*Author to whom correspondence should be addressed.
Abstract
Aims: the research aimed to determine the profile of d-dimer levels in patients confirmed positive for COVID-19 at UKI Hospital from December 2020 to September 2021
Study Design: This type of research is descriptive research with a retrospective cross-sectional research design, namely using secondary data in the form of UKI RS medical records.
Place and Duration of Study: The research was carried out in the medical records section of RS UKI from May to October 2021.
Methodology: The research samples were all medical records of patients suffering from COVID-19 with an age range of 18 to 45 years and their D-Dimer levels were checked during treatment at UKI Hospital for the period December 2020 to September 2021, totaling 148 samples. This data will be processed and analyzed using the Chi-Square Test.
Results: From the results of the study, it was found that there were 129 patients (87.2%) with COVID-19 who had normal D-Dimer levels and 19 patients (12.8%) who had elevated D-Dimer levels. Obtained a p-value of 0.677, which means that there is no statistically significant relationship between clinical symptoms and increased levels of D-Dimer in COVID-19 patients. However, there is a statistically significant relationship between the administration of anticoagulants and an increase in D-Dimer levels in COVID-19 patients with a p-value of 0.015.
Conclusion: It can be concluded that there is a significant relationship between anticoagulants and D-Dimer levels in COVID-19 patients with moderate and severe symptoms (in this case administration of anticoagulants can inhibit the increase in D-Dimer), but researchers did not find a significant relationship with mild symptoms.
Keywords: D-dimer level, anticoagulation, Covid-19