Hepatitis B Virus Infection among Chronic Renal Failure Predialysis Patients in Hodiedah, Yemen: Retrospective Study
Mansoor Shueai Al Awfi *
Department of Medical Laboratory, Faculty of Medicine and Health Sciences, Hodiedah University, Hodeidah, Yemen and Tehama Foundation for Medical - Pharmaceutical Studies and Research, Hodeidah, Yemen.
Mohammed Amood Al-Kamarany
Tehama Foundation for Medical - Pharmaceutical Studies and Research, Hodeidah, Yemen and Department of Pharmacy Practice, Faculty of Clinical Pharmacy and Tropical Medicine Center, Hodeidah University, P.O.Box 3114, Hodeidah, Yemen.
Mohammed Abdo Abkar
Department of Nursing, Faculty of Medicine and Health Sciences, Hodiedah University, Hodeidah, Yemen.
*Author to whom correspondence should be addressed.
Abstract
Background: Hepatitis viruses cause problems at almost all the stages of chronic renal failure (CRF). Most of hepatitis B virus (HBV) infected patients live in developing countries with infections rate varying from country to country.
Objective: This study aimed to find prevalence of HBV in renal failure pre- dialysis patients in renal dialysis center of Hodiedah city, Yemen.
Methods: Demographic data of 278 patients was collected retrospectively for four years and eight months from January 2011 to September 2015. All patients were examined for hepatitis B surface antigen (HBsAg) using one-step cassette device. Positive samples were confirmed by enzyme linked immunosorbent assay (ELISA). Demographic data of patients was recorded namely sex, age, education, accommodation and working.
Results: Out of 278 patients, 10 cases (3.60%) were found having HBV infection. Out of 10 positive patients, 7 cases (4.14%) were males and 3 cases (2.75%) were female. Prevalence of HBV was found in the 41- 60 age group (4.39 %) followed by 21-40 age group (3.85%). HBV was detected in 6 cases (4.72%) of 127 urban residence patients and in 4 cases (2.65%) of 151 rural residence patients. Prevalence of HBV was showed similar among educated and non-educated subjects (5 cases for each). There was a main distribution of positive cases in non-working population (10/252=3.97%) as compared to working population (0/26=0.00%).
Conclusion: HBV was detected in few CRF predialytic patients namely 3.60%. Screening of HBV in CRF predialytic patients is an effective strategy taken to ensure containment of hospital acquired infection (HAI) by isolation of patients in certain machines.
Keywords: HBV, renal, chronic, failure, Yemen