First Evidence of West Nile Virus in Hodeidah, Yemen: Clinical and Epidemiological Characteristics

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Qais Yusuf
Isra'a Al-Masrafi
Anas Al-Mahbashi
Asma'a Al-Areeqi
Mohammed Amood Al-Kamarany
Ali S. Khan


Introduction: West Nile Virus (WNV) infection is an important arthropod-borne zoonosis viral disease. This virus is neglected in Yemen especially in Hodeidah.

Aim of the Study: The purpose of this study was to detect WNV infection, determine the epidemiological and clinical characteristics within febrile patients in Hodeidah city and to determine some risk factors associated with WNV infection.

Materials and Methods: 136 febrile patients in a hospital base study were diagnosed in Center of Tropical Medicine and Infectious Diseases (CTMID), Authority of General Al-Thawara Hospital, Hodeidah, Yemen from January of 2017 to December of 2017. WNV infection was detected by enzyme linkage immune sorbent assay (ELISA) on serum samples.

Results and Discussion: The results showed that 5 cases (3.67%) were WNV – positive namely IgM that was detected in winter and spring seasons, the most prevalent antibodies of WNV were IgG namely 75 cases (55.14%). Most common symptoms were fever, headache, fatigue, weakness, arthralgia, myalgia and photophobia. The treatment based on the intravenous therapy (IV) with anti-pyritic, plasma in some cases and all cases were recovered while mortality rate was 00%.

Conclusion: WNV was detected in Hodeidah which placed in Tehama "western Yemen", as first time by our preliminary study that confirmed the evidence of WNV IgM and IG antibodies presence on 2017, in order to increase safety of diagnosis of febrile diseases, it is essential to continue surveillance of this emerging infection, suggesting that this emergence has been transported by migratory birds from wintering areas to Tehama region.

West Nile virus, Hodeidah, Yemen.

Article Details

How to Cite
Yusuf, Q., Al-Masrafi, I., Al-Mahbashi, A., Al-Areeqi, A., Al-Kamarany, M. A., & Khan, A. S. (2019). First Evidence of West Nile Virus in Hodeidah, Yemen: Clinical and Epidemiological Characteristics. International Journal of TROPICAL DISEASE & Health, 38(4), 1-9.
Original Research Article


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