Extranodal Rosai – Dorfman Disease of Oropharynx: A Rare Disease with Unusual Site of Presentation
J. Vijaya Kumar *
Department of Radiotherapy, PGIMS, Rohtak, India.
Paramjeet Kaur
Department of Radiotherapy, PGIMS, Rohtak, India.
Anil Khurana
Department of Radiotherapy, PGIMS, Rohtak, India.
Ashok K. Chauhan
Department of Radiotherapy, PGIMS, Rohtak, India.
Renuka Verma
Department of Pathology, PGIMS, Rohtak, India.
Rajeev Sen
Department of Pathology, PGIMS, Rohtak, India.
*Author to whom correspondence should be addressed.
Abstract
Rosai – Dorfman disease is a rare histiocytic disease which is most frequently seen in children and young adults. Extra nodal site of oropharynx is rare. A rare case of extranodal Rosai - Dorfman of oropharynx is described here involving a 54 year old female who presented with difficulty in swallowing. Patient underwent incisional biopsy from the growth vallecula and the diagnosis of Rosai – Dorfman disease was made. Patient was initiated on mercaptopurine and predinosolone as the general condition of the patient was not permeable to undergo any surgical procedure and radiation therapy. Unfortunately the patient had progressive dysphagia and expired in between the treatment.
Keywords: Rosai - Dorfman disease, dysphagia, mercaptopurine, radiation therapy, chemotherapy, surgery.